GEO Data Sets
=============

Provides access to data sets from gene expression omnibus [GEO
DataSets](http://www.ncbi.nlm.nih.gov/gds).

**Inputs**
- None

**Outputs**
- Expression data: Data set selected in the widget with genes or samples in rows.


[GEO DataSets](http://www.ncbi.nlm.nih.gov/gds) is a database of gene
expression curated profiles maintained by
[NCBI](http://www.ncbi.nlm.nih.gov/) and included in the [Gene
Expression Omnibus](http://www.ncbi.nlm.nih.gov/geo/info/datasets.html).
This Orange widget provides access to all its data sets and outputs a
data set selected for further processing. For convenience, each
dowloaded data set is stored locally.

![](images/geo_data_sets/GEO-Data-Sets-stamped.png)

1.  Information on the GEO data set collection. Cached data sets are the
    ones currently stored on the computer.
2.  Output features. If *Samples in rows* is selected, genes (or spots)
    will be used as attributes. Alternatively samples will be used as
    attributes. *Merge spots of same gene* averages measures of the same
    gene. Finally, in the *Data set name* you can rename the output
    data. GEO title will be used as a default name.
3.  If *Auto commit is on*, then the selected data set will be
    automatically communicated to other widgets. Alternatively, click
    *Commit*.
4.  *Filter* allows you to search for the data set. Below you see a list
    of GEO data sets with an ID number (link to the NCBI Data Set
    Browser), title, organism used in the experiment, number of samples,
    features, genes, subsets and a reference number for the PubMed
    journal (link to the article abstract).
5.  Short description of the experiment from which the data set is
    sourced.
6.  Select which *Sample Annotations* will be used in the output.

Example
-------

**GEO Data Sets** is similar to the **File** widget, since it is used to load the data. In the example below we selected *Caffeine effect: time course and dose response* dataset from the GEO data base. Do not forget to press *Commit* to output the data. We can inspect the data in *Data Table*.

![](images/geo_data_sets/GEO-Data-Sets-Example.png)